Shijiazhuang Dingmin Pharmaceutical Sciences Co., Limited is a professional
Crizotinib manufacturer.We have high R&D ability, favorable quality and competitive price.
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CAS:877399-52-5
MF:C21H22Cl2FN5O
MW: 450.343
Purity:98%
Density:1.475g/cm3
Boiling Point:599.177ºC at 760 mmHg
Flash Point:316.171ºC
Refractive Index:1.673
Appearance:White powder
Crizotinib is currently thought to exert its effects through modulation of the growth, migration, and invasion of malignant cells.Other studies suggest that crizotinib might also act via inhibition of angiogenesis in malignant tumors.
Crizotinib has an aminopyridine structure, and functions as a protein kinase inhibitor by competitive binding within the ATP-binding pocket of target kinases.
Crizotinib inhibits the c-Met/Hepatocyte growth factor receptor (HGFR) tyrosine kinase, which is involved in the oncogenesis of a number of other histological forms of malignant neoplasms.
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Dasatinib intermediates,Erlotinib intermediates ,Lapatinib Intermediates and so on.If you need,contact us.
