Erlotinib intermediates manufacturer
Vitamin B2 /Riboflavin
Appearance: white crystal or crystalline powder
Molecular Formula: C17H20N4O6
Characteristics: orange yellow crystalline powder; micro foul, bitter taste
Assay: 98.0%-101.0%
Introduction:
Vitamin B2is a yellow crystal powder,has slight special smell.
Freely soluble in water, soluble in glycerol, slightly soluble in alcohol. Used as food additives, feed and pharmaceuticals.
Function:
1. stimulate growth and cell regeneration;
2. the skin, nails, hair, normal growth;
3. to help eliminate the mouth, lips, tongue inflammation;
4. to enhance visual acuity and reduce eye fatigue;
5. the interaction with other substances to help the carbohydrates, fats, protein metabolism
COA:
| Items of Test | Limits of Test | Results of Test |
| 1.Appearance | Orange yellow crystalline powder(USP) | Confirms |
| 2.Indentification | Positive | Confirms |
| 3.Acidity or Alkalinity | Check the color of the test solution After adding the respective solutions |
Cofirms |
| 4.Lumiflavin | Absorbance of the filtrate at 440nm Does not exceed 0.025(USP);not more intense than BY6(EP/BP) |
0.009 |
| 5.Absorbance | 0.31 – 0.33 A375nm/A267nm 0.36 – 0.39 A444nm/A267nm |
0.32/0.38 |
| 6. Partical Size | 100%passes through 60 mesh sieve | Confirms |
| 7. Specific Rotation | between-115°and-135°(EP/BP/USP) | 121°(USP) 129°(EP/BP) |
| 8.Loss on Drying | ≤1.5% | 0.8% |
| 9. Heavy Metals | 10ppm | Confirms |
| 10. Residue on Ignition | ≤0.03%(USP) ≤0.1%(EP/BP) |
0.1% |
| 11.Organic Volatile Impurities | Method IV 467>(USP) | Confirms |
| 12. Assay(on dried basis) | 98.0% - 102.0%(USP) 97.0% - 10.3.0%(EP/BP) |
99.6% |
