Erlotinib intermediates manufacturer
Product name: SELEXIPAG
Appearance: white to tan powder
CAS NO.: 475086-01-2
Molecular formula: C26H32N4O4S
Molecular weight: 496.62168
Melting point: 155-158°C
Product Categories:non-prostanoid prostacyclin (PGI2) receptor agonist;Selexipag;Pharmaceuticals
Uses:
A member of the class of pyrazines that is N-(methanesulfonyl)-2-{4-[(propan-2-yl)(pyrazin-2-yl)amino]butoxy}acetamide carrying two additional phenyl substituents at positions 5 and 6 on the pyrazine ring. An orphan drug used for the tre tment of pulmonary arterial hypertension. It is a prodrug for ACT-333679 (the free carboxylic acid).
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Item |
Specifications |
Results |
|
Appearance |
White powder |
Conforms |
|
Loss on drying |
≤0.2% |
0.02% |
|
Water content(KF) |
≤0.5% |
0.03% |
|
Purity(by HPLC) |
≥98.5% |
99.00% |
|
Heavy metal |
≤15 ppm |
Conforms |
|
NMR Spectrum |
Sample correspond to that of standard preparation |
Conforms |
|
Total impurities |
≤0.3% |
Conforms |
