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MDV3100 EnzalutaMide Powder

Enzalutamide, is a nonsteroidal antiandrogen (NSAA) which is used for the treatment of metastatic, castration-resistant prostate cancer (CRPC). An up to 89% decrease in serum prostate specific antigen (PSA) levels have been reported after a month of taking the drug. Research suggests that enzalutamide may also be effective in the treatment of certain types of breast cancer. In August 2012, the United States (U.S.) Food and Drug Administration (FDA) approved enzalutamide for the treatment of CRPC.

Product Name: Enzalutamide (MDV3100)
Synonyms: MDV-3100;4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-N-methylbenzamide;4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide;4-{3-[4-cyano-3-(trifluoroMethyl)phenyl]-5,5-diMethyl-4-oxo-2-sulfanylideneiMidazolidin-1-yl}-2-fluoro-N-MethylbenzaMide;EnzalutaMide;MDV3100 (EnzalutaMide);MDV 3100,4-[3-[4-Cyano-3-(trifluoroMethyl)phenyl]-5,5-diMethyl-4-oxo-2-thioxo-1-iMidazolidinyl]-2-fluoro-N-MethylbenzaMide;4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N
CAS: 915087-33-1
MF: C21H16F4N4O2S
MW: 464.4359528
EINECS: 805-022-1
Product Categories: Apoptosis;Aromatics;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Inhibitor
Mol File: 915087-33-1.mol
Appearance  white powder
MOQ 1g

COA of Enzalutamide

Item Specification
Specific rotation +39.5 to +41.5°
State of solution(transmittance) Clear 98.0% min.
Chloride[cl] 0.020% max.
Ammonium [NH4] 0.02% max.
Sulfate[SO4] 0.020% max
Iron[Fe] 10ppm max.
Heavy metals [Pb] 10ppm max
Arsenic[As2O3] 1ppm max
Other amino acids Chromatographically not detectable
Loss on drying 0.20% max.
Residue on ignition[sulfated] 0.10% max.
Assay 99.0% min

HS CODE: 29339900

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