Cabozantinib (S)-malate

CAS No.:1140909-48-3

Other Names:Cabozantinib malate (XL184)

MF:C32H30FN3O10

Place of Origin: China (Mainland)

Type:Vitamins, Amino Acids and Coenzymes

Grade Standard:Medicine Grade

Model Number:M01-CAS 1140909-48-3

Purity:99%min

Appearance:white powder

Molecular formula:C32H30FN3O10

Molecular weight:635.59300

Exact Mass:635.19200

PSA:193.61000

LogP:4.59340

Supply Ability

100 Kilogram/Kilograms per Month

Packaging & Delivery

Packaging Details

Within 3-5 days after receiving your payment

Port ;Any port in China

Lead Time :Within 3-5 days after receiving your payment

Product Description

 Cabozantinib S-Malate cas no 1140909-48-3

Cabozantinib is a small molecule C-Met modulator. Cabozantinib acts as a potent multitargeted VEGFR2, Met, FLT3, Tie2, Kit and Ret inhibitor with IC50 of 0.035, 1.8, 14.4, 14.3 and 4.6 nM for VEGFR2, Met, FLT3, Tie2 and Kit, respectively. Cabozantinib shows dose-dependent inhibition of tumor growth and tumor regression, associated with disruption of the tumor vasculature and extensive tumor cell apoptosis.